Minoxidil Cyclodextrin Complexes and Their Inclusion in Transfersomes for the Enhancement of Therapeutic Effect on Androgenic Alopecia

August 2024 in “ Journal of Drug Delivery Science and Technology ”

Xia Kong, Xiaoya Pang, Ruifen Wang, Qian Zhang, Xiangqi Kong, H. Li, Xiaxia Liu, Shaosan Kang, Hao Sui, Qingping Tian

minoxidil cyclodextrin transfersomes androgenic alopecia sulfobutylether-β-cyclodextrin molecular docking drug loading encapsulation efficiency MXD CD SBE-β-CD DL EE AGA

Studysummary In this study, the researchers reported that minoxidil-loaded transfersomes using a cyclodextrin strategy significantly increased drug stability, skin permeation, and hair regrowth in a mouse model of androgenetic alopecia compared to traditional formulations and commercial tinctures.

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