The Preparation of High Minoxidil Loaded Transfersomes and Its Gel for Effective Topical Treatment of Alopecia

    April 2023 in “ Journal of Drug Delivery Science and Technology ”
    Ying Sun, Yongxiang Zhang, Xiaxia Liu … Qingping Tian
    Studysummary This study reported that optimized transfersomes and their gel form significantly improved transdermal delivery and hair growth promotion of minoxidil in C57BL/6 mice compared to commercial formulations.
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    Research cited in this study 27

    1. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    2. Neural Progenitor Cell-Derived Nanovesicles Promote Hair Follicle Growth via miR-100 Journal of nanobiotechnology · 2021
    3. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    4. Exploring the Potential of Minoxidil Tretinoin Liposomal-Based Hydrogel for Topical Delivery in the Treatment of Androgenic Alopecia Cutaneous and Ocular Toxicology · 2019
    5. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    6. Scaffold-Assisted Artificial Hair Implantation in a Rat Model JAMA Facial Plastic Surgery · 2017
    7. Formulation and Optimization of Transfersome Containing Minoxidil and Caffeine Journal of Drug Delivery Science and Technology · 2017
    8. Alginate-Based Hydrogel Containing Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex for Topical Alopecia Treatment Journal of Pharmaceutical Sciences · 2017
    9. A Novel Approach for Follicular Delivery of Minoxidil for Treatment of Alopecia Journal of Drug Delivery Science and Technology · 2017
    10. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    11. Hair-Growth Stimulation by Conditioned Medium from Vitamin D3-Activated Preadipocytes in C57BL/6 Mice Life sciences · 2015
    12. Drug Discovery for Alopecia: Gone Today, Hair Tomorrow Expert Opinion on Drug Discovery · 2015
    13. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    14. Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia International Journal of Nanomedicine · 2014
    15. New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment Drug Development and Industrial Pharmacy · 2014
    16. Regenerative Medicine and Hair Loss: How Hair Follicle Culture Has Advanced Our Understanding of Treatment Options for Androgenetic Alopecia Regenerative Medicine · 2013
    17. Niosomes as a Vesicular Carrier for Topical Administration of Minoxidil: Formulation and In Vitro Assessment Drug Delivery and Translational Research · 2013
    18. Preparation and Characterization of Minoxidil Loaded Nanostructured Lipid Carrier Gel for Effective Treatment of Alopecia Journal of The Saudi Pharmaceutical Society · 2013
    19. Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model Journal of Dermatological Science · 2013
    20. 5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment Journal of Ethnopharmacology · 2011
    21. Fructus Panax Ginseng Extract Promotes Hair Regeneration in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    22. The Effects of Particle Properties on Nanoparticle Drug Retention and Release in Dynamic Minoxidil Foams International Journal of Pharmaceutics · 2010
    23. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    24. Liposomes And Niosomes As Potential Carriers For Dermal Delivery Of Minoxidil Journal of Drug Targeting · 2007
    25. Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    26. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    27. Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994

    Related research 8

    1. The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review PubMed · 2019
    2. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    3. Male Androgenetic Alopecia Treated with Microneedling Alone or Associated with Injectable Minoxidil by Microinfusion of Drugs into the Skin Surgical and Cosmetic Dermatology · 2016
    4. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987
    5. A Trial of 1% Minoxidil Used Topically for Severe Alopecia Areata PubMed · 1986
    6. Topical Minoxidil in the Treatment of Alopecia Areata Plastic & Reconstructive Surgery · 1985
    7. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984
    8. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983