A Novel Approach for Follicular Delivery of Minoxidil for Treatment of Alopecia

    July 2017 in “ Journal of Drug Delivery Science and Technology ”
    Mohip Maitra, Amit K. Goyal, Goutam Rath
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    TLDR Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
    In 2017, researchers Maitra, Goyal, and Rath developed a new method for delivering minoxidil, a common alopecia treatment, directly to hair follicles. They created a minoxidil-loaded microemulsion, characterized by a globule size of 41.0nm, a zeta potential of +28.22mV, and a transmittance of 98.1%. The microemulsion showed an in-vitro release of 68.5% after 24 hours and 67.5% drug retention inside the hair shaft in ex-vivo studies. The formulation significantly altered the follicular response in a 5-Fluorouracil induced alopecia model. The study concluded that this novel approach could be a promising treatment for alopecia and other follicular diseases.
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      in Progress Pictures  520 upvotes 2 years ago
      This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.

      community Minoxidil doesn’t work over night.

      in Is this regrowth?  196 upvotes 4 months ago
      Minoxidil requires at least 6 months to show results and may not work for everyone. Combining it with Finasteride can improve outcomes, but stopping Minoxidil can result in losing any regrowth.

      community The Fear of Oral Minoxidil is Overblown

      in Research/Science  256 upvotes 4 months ago
      Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 1 year ago
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