TLDR Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
In 2017, researchers Maitra, Goyal, and Rath developed a new method for delivering minoxidil, a common alopecia treatment, directly to hair follicles. They created a minoxidil-loaded microemulsion, characterized by a globule size of 41.0nm, a zeta potential of +28.22mV, and a transmittance of 98.1%. The microemulsion showed an in-vitro release of 68.5% after 24 hours and 67.5% drug retention inside the hair shaft in ex-vivo studies. The formulation significantly altered the follicular response in a 5-Fluorouracil induced alopecia model. The study concluded that this novel approach could be a promising treatment for alopecia and other follicular diseases.
29 citations,
June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
103 citations,
December 2011 in “Journal of the American Academy of Dermatology” Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
166 citations,
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20 citations,
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73 citations,
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4 citations,
May 2022 in “Future Journal of Pharmaceutical Sciences” Melatonin-loaded microemulsion could be a promising treatment for hair loss.
40 citations,
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21 citations,
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72 citations,
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10 citations,
February 2021 in “International Journal of Nanomedicine” Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.
