Is it possible to make a propylene glycol free Minoxidil + Tretenoin solution?
    Minoxidil 11/12/2025

    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Tretinoin →

    the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Minoxidil (topical)
    💧 Tretinoin (topical)
    the tone is 😐 neutral.

    Other terms

    Creating a propylene glycol-free Minoxidil and Tretinoin solution to reduce skin irritation and enhance effectiveness. An emulsifier like lecithin can help mix Tretinoin properly, and Minoxidil foam is an alternative without propylene glycol.
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      community Minoxidil+ Spray by keep does it contain propylene glycol?

       1 upvotes 1 year ago
      The user is using Dutasteride and oral Minoxidil for hair regrowth and is considering adding topical Minoxidil but is allergic to propylene glycol, which is present in the product they found. They need a solution with tretinoin that does not contain propylene glycol.

      community Thoughts on 5% Topical Minoxidil with 0.01% Tretinoin serum

       3 upvotes 1 year ago
      The conversation discusses using a 5% Topical Minoxidil with 0.01% Tretinoin serum for hair loss, noting its lack of propylene glycol to avoid itchiness and greasiness. Users share experiences with different Minoxidil formulations and discuss the effectiveness and stability of Tretinoin in various forms.

      community Is my topical Minoxidil solution optimal enough?

       1 upvotes 10 months ago
      The user is using a 5% minoxidil solution with low propylene glycol and 1 mg of oral finasteride daily but is still experiencing hair shedding, especially at the temples and front. They are concerned about absorption issues and considering adding tretinoin to improve results.

      community My personal experience/observations fighting AGA seriously for 5 years

       50 upvotes 1 year ago
      Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

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