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GlossaryCluster of Differentiation (CD)

system for identifying cell surface molecules, especially on white blood cells

Cluster of Differentiation (CD) refers to a system used to identify and classify surface molecules on cells, particularly white blood cells, which are critical for the immune system. These molecules serve as markers that help differentiate between various cell types and their functions, and are often used in medical diagnostics and research to understand immune responses and diseases.

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Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

research Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

235 citations, January 2011 in “Journal of Clinical Investigation”

Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.

research The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle

165 citations, September 2001 in “Genes & development”

CDP is crucial for lung and hair follicle cell development.

research Skin CD4+ Memory T Cells Exhibit Combined Cluster-Mediated Retention and Equilibration with the Circulation

155 citations, May 2016 in “Nature communications”

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

research Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors

153 citations, January 2001 in “Science”

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism

135 citations, December 2006 in “PLoS Medicine”

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

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community Can anyone tell me if this might be dangerous or good for my hair/head/body ?

in Question 6 years ago

A user is asking if a new hair product, Cypress Premium Vials Energy and Cypress Premium Shampoo Energy, could be dangerous or worsen their hair condition. The product contains various ingredients including water, alcohol, menthyl lactate, and several extracts.

community FCE 28260: A Forgotten 5α-Reductase Inhibitor

in Research 330 upvotes 2 months ago

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

community Oxytocin, empathy, hair, and cinnamon

in General 87 upvotes 3 months ago

Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 4 months process, 3740 grafts

in Journals / Progress Pictures 99 upvotes 3 months ago

A user shared their 4-month hair transplant progress with 3740 grafts, showing before and after pictures. They had a generally good experience, except for the anesthesia part.

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