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    Glossary CD4

    protein on immune cells crucial for signaling and HIV entry

    CD4 is a type of protein found on the surface of certain immune cells, such as T-helper cells. These cells play a crucial role in the immune system by signaling other cells to perform their functions. CD4 is also the primary receptor that HIV uses to enter and infect these immune cells, which can lead to a weakened immune system.

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    1. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    2. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism PLoS Medicine · 2006 · 135 citations
    3. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells that Repopulate Epidermis After UVB Exposure 1998 · 99 citations
    4. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002 · 77 citations
    5. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    6. CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung Frontiers in Pharmacology · 2014 · 39 citations
    7. <i>In vivo </i>CD44‐CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance European Journal of Immunology · 2006 · 33 citations
    8. Anti-CD44-mediated blockade of leukocyte migration in skin-associated immune diseases Journal of Leukocyte Biology · 2007 · 30 citations
    9. The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability Stem cells · 2013 · 28 citations
    10. Diphencyprone and topical tacrolimus as two topical immunotherapeutic modalities. Are they effective in the treatment of alopecia areata among Egyptian patients? A study using CD4, CD8 and MHC II as markers Journal of dermatological treatment · 2010 · 13 citations
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