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GlossaryCD4

protein on immune cells crucial for signaling and HIV entry

CD4 is a type of protein found on the surface of certain immune cells, such as T-helper cells. These cells play a crucial role in the immune system by signaling other cells to perform their functions. CD4 is also the primary receptor that HIV uses to enter and infect these immune cells, which can lead to a weakened immune system.

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research Skin CD4+ Memory T Cells Exhibit Combined Cluster-Mediated Retention and Equilibration with the Circulation

155 citations, May 2016 in “Nature communications”

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism

135 citations, December 2006 in “PLoS Medicine”

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

research The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure

99 citations, April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair follicles help skin immune recovery after UVB exposure.

research PD-1+ CXCR5− CD4+ T Cells Are Correlated with the Severity of Systemic Lupus Erythematosus

71 citations, May 2019 in “Rheumatology”

Tph cells are linked to the severity of systemic lupus erythematosus.

CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung

research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung

39 citations, May 2014 in “Frontiers in Pharmacology”

Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.

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community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 4 weeks ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community The Cure isn't 5 years away; it's already here.

in Research/Science 1001 upvotes 3 months ago

PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.