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GlossaryCD49f

protein aiding cell adhesion and migration, crucial for tissue maintenance

CD49f, also known as Integrin alpha-6 or ITGA6, is a protein found on the surface of certain cells that helps them stick to their surroundings. It plays a crucial role in cell adhesion, migration, and signaling, which are important for processes like wound healing and the maintenance of tissues, including hair follicles.

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research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance

11 citations, March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

A specific group of skin stem cells was found to help maintain hair follicle cells.

research Differential Expression of Stem Cell Markers in Human Follicular Bulge and Interfollicular Epidermal Compartments

28 citations, March 2010 in “Histochemistry and Cell Biology”

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

23 citations, June 2012 in “PLOS ONE”

KLF4 is important for maintaining skin stem cells and helps heal wounds.

research Hair Follicle Stem Cells Isolated from Newborn Yangtze River Delta White Goats

16 citations, February 2019 in “Gene”

Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.

research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

6 citations, May 2013 in “PloS one”

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

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