Platelet-Rich Plasma in Alopecia Areata and Primary Cicatricial Alopecias: A Systematic Review

    November 2022 in “ Frontiers in Medicine
    Kasama Tejapira, Tanat Yongpisarn, Nawara Sakpuwadol, Poonkiat Suchonwanit
    TLDR PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.
    This systematic review assessed the efficacy of platelet-rich plasma (PRP) in treating alopecia areata (AA) and primary cicatricial alopecias (PCAs) by analyzing 32 studies with 621 AA patients and 19 PCA patients. PRP showed promising results in AA, especially in mild cases, with better efficacy than placebo and similar efficacy to intralesional triamcinolone acetonide (TA). PRP also had benefits as an adjunctive treatment. However, its efficacy in PCAs was less clear due to limited studies and variable responses. The review emphasizes the need for more high-quality, randomized controlled trials to confirm PRP's therapeutic potential in these conditions.
    Discuss this study in the Community →

    Research cited in this study

    50 / 50 results

    Related Community Posts Join

    6 / 79 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community When are we getting a cure to hair loss?

      in Chat 1 year ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community To my fellow under 20s that are balding

      in Chat  127 upvotes 1 year ago
      The conversation is about young men under 20 experiencing hair loss. They discuss their experiences and treatments used, including finasteride (fin) and minoxidil (min).

      community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

      in Research/Science  3 upvotes 1 year ago
      The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

    Similar Research

    5 / 1000+ results