Hypothesis: Platelet-Rich Plasma as an Adjunct Therapy for Eczema Targeting Inflammation, Skin Barrier Repair, and Chronic Recurrence

    October 2025 in “ Frontiers in Immunology ”
    Ju Tian, Jing Ding, Huimin You … Biao Cheng
    Studysummary This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.
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    Research cited in this study 11

    1. Alopecia Areata: Pathogenesis, Diagnosis, And Therapies MedComm · 2025
    2. Novel Method for Preparation of Autologous Leucocyte Rich Platelet Rich Plasma (L-PRP) Under Closed System and Assessment of Its Clinical Efficacy in Androgenic Alopecia: A Retrospective Cohort Study Journal of Plastic Reconstructive & Aesthetic Surgery · 2025
    3. Evaluating Anti-Inflammatory Potential of Platelet-Rich Plasma in Scarring Alopecia: A Systematic Review Journal of Drugs in Dermatology · 2024
    4. Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action Biomedicines · 2023
    5. Platelet-Rich Plasma for the Treatment of Plaque Psoriasis: A Systematic Review Cureus · 2023
    6. Duo-Role Platelet-Rich Plasma: Temperature-Induced Fibrin Gel and Growth Factors' Reservoir for Microneedles to Promote Hair Regrowth Journal of Advanced Research · 2023
    7. Platelet-Rich Plasma in Alopecia Areata and Primary Cicatricial Alopecias: A Systematic Review Frontiers in Medicine · 2022
    8. Can Platelet-Rich Plasma Reduce the Burden of Inflammatory Skin Diseases Such as Psoriasis and Atopic Dermatitis? Cureus · 2021
    9. Successful Treatment of Corticosteroid-Induced Rosacea-Like Dermatitis with Platelet-Rich Plasma Mesotherapy: Report of Seven Cases Dermatology and Therapy · 2021
    10. Evaluation of Platelet-Rich Plasma on Hair Regrowth and Lesional T-Cell Cytokine Expression in Alopecia Areata: A Randomized Observer-Blinded, Placebo-Controlled, Split-Head Pilot Study Journal of The American Academy of Dermatology · 2020
    11. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside Frontiers in immunology · 2020