Frontal Fibrosing Alopecia in Asians: A Retrospective Clinical Study

    October 2019 in “ International Journal of Dermatology ”
    Poonkiat Suchonwanit, Kallapan Pakornphadungsit, Kanchana Leerunyakul, Saranya Khunkhet, Tueboon Sriphojanart, Salinee Rojhirunsakool
    Image of study
    TLDR The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.
    The retrospective clinical study by Suchonwanit et al. investigated Frontal fibrosing alopecia (FFA) in 56 Thai patients, predominantly female (96.4%), with an average age of onset at 51.3 years. The study found that all patients had frontotemporal hairline recession, and a significant majority (87.5%) also suffered from eyebrow loss. Trichoscopic examination of 35 patients revealed common signs such as follicular dropout, perifollicular erythema, and lonely hair. The most effective treatment for disease stabilization was a combination of topical corticosteroids with hydroxychloroquine (79.3% stabilization) or finasteride (73.3% stabilization). The study suggested that FFA in Asians has mixed clinical patterns and that environmental factors and personal care products might contribute to the condition. It also highlighted the effectiveness of combination therapy in managing FFA, despite the study's limitations, including its retrospective design, single-center approach, and lack of a control group.
    Discuss this study in the Community →

    Research cited in this study

    21 / 21 results

    Related Community Posts Join

    6 / 378 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 2 weeks ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Related Research

    6 / 6 results