Co-Localization of Alopecia Areata and Lichen Planopilaris in a Patient Receiving Immunosuppressants: A Rare Case

    July 2020 in “ Journal of cosmetic dermatology ”
    Ramin Mofarrah, Ramina Mofarrah, Kousar Jahani Amiri, Maryam Ghasemi
    Image of study
    TLDR A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.
    A 37-year-old woman with a history of hypothyroidism and lupus erythematosus arthritis, who was on long-term immunosuppressive treatment, developed both alopecia areata (AA) and lichen planopilaris (LPP). Despite her immunosuppressive regimen, she experienced general scalp alopecia, particularly on the vertex, with mild itching and trichodynia. Treatment with Minoxidil 5%, Clobetasol solution, and an increased dose of Azathioprine led to the resolution of follicular hyperkeratosis and scalp erythema, and hair regrowth was observed in AA spots after 3 months. This case highlighted the potential mutual immunopathogenesis of AA and LPP and the possibility of new autoimmune diseases emerging even under immunosuppressive therapy.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 3 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community C’est terrible - at my wits end

      in Female  445 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community To anyone that is still not seeing results on the big 3…

      in Treatment  105 upvotes 2 years ago
      User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

    Related Research

    7 / 7 results