Factors Affecting the Severity of Central Centrifugal Cicatricial Alopecia

    Poonkiat Suchonwanit, Clare E. Hector, Ghada A. Bin Saif, Amy J. McMichael
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    TLDR Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.
    This study aimed to identify factors associated with the severity of central centrifugal cicatricial alopecia (CCCA) in African-American women. The duration of hair loss was found to be strongly positively associated with the degree of hair loss, reflecting the progressive nature of CCCA. Androgen-related conditions were prevalent in those affected with CCCA. The study suggests that early recognition and proper medical treatment are the best ways to protect and support hair regrowth. Patients report improvement with intralesional corticosteroids and topical steroids, but larger, prospective, controlled studies are required to evaluate the etiology of and treatment options for this condition. The study also suggests that hair care practices, such as avoiding potentially damaging hairstyles and excessive heat, should be advised.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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