Factors Affecting the Severity of Central Centrifugal Cicatricial Alopecia

    Poonkiat Suchonwanit, Clare E. Hector, Ghada A. Bin Saif, Amy J. McMichael
    Image of study
    TLDR Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.
    This study aimed to identify factors associated with the severity of central centrifugal cicatricial alopecia (CCCA) in African-American women. The duration of hair loss was found to be strongly positively associated with the degree of hair loss, reflecting the progressive nature of CCCA. Androgen-related conditions were prevalent in those affected with CCCA. The study suggests that early recognition and proper medical treatment are the best ways to protect and support hair regrowth. Patients report improvement with intralesional corticosteroids and topical steroids, but larger, prospective, controlled studies are required to evaluate the etiology of and treatment options for this condition. The study also suggests that hair care practices, such as avoiding potentially damaging hairstyles and excessive heat, should be advised.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 55 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

    Related Research

    5 / 5 results