Evaluation of Platelet-Rich Plasma in the Treatment of Alopecia Areata

May 2018 in “ Journal of the Egyptian Womenʼs Dermatologic Society ”

Hassan E. Fayed, Moustafa A. Elsaied, Marwa R. Faraj

platelet-rich plasma alopecia areata PRP hair regrowth saline placebo scalp treatment efficacy safety quality of life side effects

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Studysummary This study found that platelet-rich plasma treatment was effective and safe for promoting hair regrowth in mild cases of alopecia areata, with significant improvements in quality of life compared to placebo.

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Research cited in this study

14 / 14 results

research Factors Associated With Severity Of Alopecia Areata

63 citations , January 2017 in “Annals of Dermatology”

More research is needed to understand alopecia areata severity.

research Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation

62 citations , October 2016 in “Dermatologic Therapy”

This study found that platelet-rich plasma was more effective for treating alopecia areata than topical 5% minoxidil, leading to earlier hair regrowth and reduction in hair abnormalities.

research Successful Treatment of Corticosteroid-Resistant Ophiasis-Type Alopecia Areata with Platelet-Rich Plasma

30 citations , August 2015 in “JAAD case reports”

This case report describes a patient with corticosteroid-resistant ophiasis alopecia areata who experienced prompt hair regrowth after receiving platelet-rich plasma injections.

research Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience

61 citations , January 2015 in “Indian Journal of Plastic Surgery”

This study found that platelet-rich plasma may have a role in treating chronic alopecia areata, but more long-term follow-up studies are needed to confirm its effectiveness and success rate.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

research Platelet-Rich Plasma Injection Is Effective and Safe for the Treatment of Alopecia

45 citations , March 2013 in “European Journal of Plastic Surgery”

In this retrospective study, PRP injections for alopecia were found to improve hair volume and quality, with high patient satisfaction, particularly in those with less than 2 years of hair loss.

research Alopecia Areata Update

85 citations , October 2012 in “Dermatologic Clinics”

This article reviews recent updates on alopecia areata, focusing on its causes, clinical presentation, and treatment options, and provides treatment plans by patient age and disease extent, but reports no new clinical results.

research Commentary on Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

13 citations , July 2012 in “Dermatologic Surgery”

Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

research Hair Mesotherapy: A Non-Surgical Procedure for Hair Loss

5 citations , January 2012 in “Hair therapy & transplantation”

Hair mesotherapy might help with certain types of hair loss but lacks strong scientific proof and has some risks.

research Alopecia Areata Update

244 citations , January 2010 in “Journal of the American Academy of Dermatology”

This review discusses treatment options for alopecia areata and suggests tailored treatment plans, noting the challenges posed by spontaneous remission and limited high-quality clinical trials.

research Alopecia Areata Update

391 citations , January 2010 in “Journal of The American Academy of Dermatology”

This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.

research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro

51 citations , February 2009 in “Journal of dermatological science”

In this study, β-catenin overexpression in human hair outer root sheath cells increased the expression of Pitx2, which activated the follicular differentiation pathway, suggesting Pitx2's potential role as a modulator in hair growth control.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.