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Glossary safety

condition of being protected from harm or adverse effects

Safety refers to the condition of being protected from or unlikely to cause danger, risk, or injury. In the context of hair and alopecia, safety might involve using products and treatments that have been tested and proven not to cause harm to the scalp or hair follicles, ensuring that they do not exacerbate hair loss or cause adverse reactions.

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Research

5 / 1000+ results

research Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

222 citations , September 2016 in “JCI insight”

This research overview highlights that although JAK inhibitors show promise as potential treatments for alopecia areata based on recent insights into the disease mechanism, their efficacy has not yet been thoroughly evaluated in a systematic manner.

research Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection

176 citations , June 2016 in “PLoS ONE”

In these initial clinical studies, NAP monotherapy showed significant reductions in HBsAg levels among patients with chronic HBV, suggesting potential as part of future combination therapies.

research Safety of Human Papillomavirus Vaccines: A Review

149 citations , April 2013 in “Drug Safety”

research Safety of testosterone treatment in postmenopausal women

81 citations , May 2007 in “Fertility and Sterility”

This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.

research Safety of dermatologic medications in pregnancy and lactation

73 citations , March 2014 in “Journal of The American Academy of Dermatology”

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

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Community Join

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community Efficacy and Safety of Oral Dutasteride 0.5 mg Combined with Oral Minoxidil 2.5 mg for Male Androgenetic Alopecia: A Retrospective Cohort Study

93 upvotes 1 month ago

Oral dutasteride 0.5 mg combined with oral minoxidil 2.5 mg is highly effective for male androgenetic alopecia, showing over 60% improvement and 98% stabilization at 6 months, with low adverse event rates. Patients with severe baseline conditions respond better and faster to this treatment.

community PP405 2a study was a safety study. Some rational explaining.

22 upvotes 1 year ago

The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

community Study: You can safely conceive on Dutasteride

in Research/Science 95 upvotes 1 year ago

Dutasteride is considered safe for conception, with semen concentrations being too low to cause harm. Users discuss switching between dutasteride and finasteride, with some experiencing side effects like acne and heart issues, and advice is given to maintain a consistent treatment regimen.

community Kintor long term safety phase 3

in Research/Science 66 upvotes 1 year ago

Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

community Effectiveness and Safety of Hair Growth Formulation Containing Tectona grandis L.f (Teak) Leaf Extract

in Chat 33 upvotes 1 year ago

Teak leaf extract shows potential as a mild hair growth promoter for androgenic alopecia, with similar positive trends to minoxidil but without significant side effects. It can be made at home using dried teak leaves and ethanol, though its effectiveness compared to other treatments like finasteride is debated.

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Learn

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learn Latanoprost

Can latanoprost be safely applied to the scalp, or is it only for eyelashes? Latanoprost is not approved for use on the scalp and its safety there has not been established: the only human scalp evidence is one 24-week pilot trial in 16 men, and clinicians flag irritation, skin darkening and unknown absorption over a large area as open risks.

learn Setipiprant

Can Setipiprant be used safely by women or people undergoing gender transition? Setipiprant's safety for women and those in transition is not well-studied.

learn sh-Polypeptide-7

Are there any safety concerns or allergic reactions associated with sh-Polypeptide-7 in topical hair products? There are no published human studies on sh-Polypeptide-7 itself, so its safety is unestablished; research on cosmetic peptides as a class reports low irritation and rare allergy, and dermatologists advise patch testing a new scalp product.

learn Hydrocortisone

How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it? The over-the-counter hydrocortisone label sets the limits: a thin film on the affected patch, no more than three or four times a day, and no longer than seven days without a doctor's direction — and the scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.

learn Spironolactone

Who can safely use spironolactone for hair thinning and androgen-related hair loss? Women with androgen-related hair loss can safely use spironolactone under medical supervision.

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