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Glossary Area Under the Curve

graphical representation of total exposure to a drug over time

Area Under the Curve (AUC) is a statistical measure used to quantify the overall exposure of a drug in the bloodstream over time. It is often used in pharmacokinetics to assess the efficacy and safety of medications by plotting the concentration of the drug against time and calculating the area beneath this plot. This helps in understanding how long and how well a drug stays active in the body.

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Research

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research Hair Growth Promoting Activity of Cedrol Nanoemulsion in C57BL/6 Mice and Its Bioavailability

12 citations , March 2021 in “Molecules”

This study found that a cedrol nanoemulsion improved hair growth and bioavailability compared to an ointment, demonstrating enhanced efficacy in vitro and in vivo.

research Prostate specific antigen (PSA) in diagnosis of polycystic ovarian syndrome – a new insight

6 citations , July 2016 in “Gynecological Endocrinology”

This study found that women with PCOS have higher total PSA levels than controls, and the total PSA level correlates positively with testosterone and free androgen index.

research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride

1 citations , October 2023 in “Journal of personalized medicine”

In this study, researchers investigated genetic variants in pharmacogenes affecting tadalafil and finasteride pharmacokinetics, finding fed volunteers had higher drug exposure than fasting individuals, but genetic variation did not significantly impact pharmacokinetics after correcting for multiple comparisons.

research Bioequivalance of single oral administration of finasteride tablet and capsule in healthy volunteers

January 2004

This study found that the finasteride tablet and capsule are bioequivalent to the control finasteride tablet in healthy volunteers.

research 200 Deep learning model to predict sentinel lymph node status in melanoma patients

April 2023 in “Journal of Investigative Dermatology”

This study suggests that histological features of primary melanoma can partially predict lymph node metastasis using AI, achieving a best prediction AUROC of 0.65.

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Community Join

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community What Are the Technicalities of Curved Hair Transplantation?

4 upvotes 6 months ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 35 upvotes 2 years ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community Just under a year progress (topical fin/min .3/6%)

in Progress Pictures 612 upvotes 2 years ago

A user shared their positive experience with hair regrowth using topical finasteride and minoxidil, despite initial side effects. They are transitioning to oral finasteride and minoxidil for convenience and are optimistic about continued progress.

community Currently Trending Twitter Post: Clascoterone Hailed as New Cure

1897 upvotes 9 months ago

Clascoterone is being discussed as a promising new hair loss treatment, showing significant improvement in trials. Despite this, skepticism persists about its effectiveness, cost, and side effects, with some users preferring minoxidil and finasteride.

community The DEFINITIVE cure for hairloss

285 upvotes 1 year ago

The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

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Learn

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learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

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Clinics

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Hair Transplant
Cosmagic Clinic under Dr.Asif BhattiLahore · PK

Experts

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Hair Transplant Surgeon
Dr. Theo Birch, MBBS, FRACS
Central Coast, NSW, Australia

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Dr. Theo Birch, MBBS, FRACS