Oral Minoxidil Therapy in Hair Loss: Where Do We Stand?

    November 2023 in “ Current Dermatology Reports
    Ghadah Alhetheli
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    TLDR Oral minoxidil is effective for various hair loss types and may improve male sexual function, but aspirin can reduce its effectiveness.
    The review discusses the effectiveness and safety of oral minoxidil (OM) in treating various types of hair loss, including androgenic alopecia (AGA). Studies suggest that OM, in doses ranging from 0.625 to 2.5 mg daily, is effective in treating male pattern hair loss, and can be gradually increased up to 5 mg/day. OM has shown effectiveness in both sexes and in pediatric patients. It is more advantageous than topical minoxidil due to its convenience, cost-effectiveness, and compatibility with adjuvant co-therapy. Unlike 5α-reductase inhibitors, which are associated with male sexual dysfunction, OM improves male sexual function due to its vasodilator effect. The document also mentions the potential of OM in treating pediatric hair diseases, tractional alopecia, chemotherapy-induced alopecia, and female pattern hair loss. However, the use of low-dose daily aspirin reduces the efficacy of topical minoxidil in androgenetic alopecia patients.
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      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Oral min 2.5mg closing in on 3 months

      in Progress Pictures  372 upvotes 1 year ago
      _the_orange_box_'s experience using oral minoxidil, with discussion about finasteride and the potential side effects of both treatments. Other users shared their own experiences related to hair loss treatments.

      community C’est terrible - at my wits end

      in Female  449 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

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