Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study

    October 2020 in “ Dermatologic Therapy ”
    Farid Masoud, Hamideh Azimi Alamdari, Solmaz Asnaashari … Yousef Javadzadeh
    Studysummary This study found that a topical herbal solution significantly increased hair diameter and density in men with androgenetic alopecia compared to minoxidil after 36 weeks of treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 37

    1. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    2. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    3. Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies Archives of Dermatological Research · 2017
    4. Guidelines on the Use of Finasteride in Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
    5. Selected Disorders of Skin Appendages: Acne, Alopecia, Hyperhidrosis Medical Clinics of North America · 2015
    6. Hair Growth: Focus on Herbal Therapeutic Agents Current Drug Discovery Technologies · 2015
    7. Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study Pharmacotherapy · 2015
    8. Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin PLOS ONE · 2015
    9. The Androgenic Alopecia Protective Effects of Forsythiaside-A and the Molecular Regulation in a Mouse Model Phytotherapy Research · 2015
    10. Contribution of Hair Density and Hair Diameter to the Appearance and Progression of Androgenetic Alopecia in Japanese Men British Journal of Dermatology · 2014
    11. Common Dermatologic Conditions Medical Clinics of North America · 2014
    12. Evidence for a Polygenic Contribution to Androgenetic Alopecia British Journal of Dermatology · 2013
    13. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    14. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    15. Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract Phytotherapy Research · 2012
    16. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    17. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    18. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    19. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
    20. Hair Growth and Rejuvenation: An Overview Journal of Dermatological Treatment · 2010
    21. Male Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2010
    22. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    23. Androgenetic Alopecia: Quality of Life and Associated Lifestyle Patterns International Journal of Trichology · 2010
    24. Serenoa Repens: Does It Have Any Role in the Management of Androgenetic Alopecia? Journal of Cutaneous and Aesthetic Surgery · 2009
    25. Finasteride Induced Gynecomastia: Case Report and Review of the Literature International Journal of Trichology · 2009
    26. The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis International Journal of Dermatology · 2008
    27. Male Pattern Baldness: Current Treatments, Future Prospects Drug Discovery Today · 2008
    28. Follicular Miniaturization in Female Pattern Hair Loss: Clinicopathological Correlations British Journal of Dermatology · 2006
    29. Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgens Journal of Investigative Dermatology Symposium Proceedings · 2005
    30. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    31. Unilateral Gynecomastia Induced by Treatment With 1 mg of Oral Finasteride Archives of Dermatology · 2002
    32. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    33. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999
    34. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    35. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    36. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996
    37. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990

    Related research 5

    1. A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss PubMed · 2022
    2. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    3. Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study Dermatologic Therapy · 2020
    4. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    5. Off-Label Use of Topical Minoxidil in Alopecia: A Review American Journal of Clinical Dermatology · 2019