New 2025 study: high dose oral minoxidil (up to 10mg) Research/Science 9/24/2025
High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.
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6 / 1000+ resultscommunity Continuous Shedding 4 Months into Minoxidil and Finasteride Treatment - Is This Normal?
The user is experiencing hair shedding after using oral finasteride and topical minoxidil, questioning if this is normal. They are concerned about thinning at the hairline despite using these treatments.
community Experience with only Minoxidil and Nizoral
Minoxidil and Nizoral alone are unlikely to stop hair loss effectively, as they do not address the root cause, which is often DHT. Many users suggest incorporating a 5AR inhibitor like finasteride or dutasteride for better results, despite concerns about potential side effects.
community You may not have the enzyme for topical minoxidil to work - a rarely talked about impact
Some people may not respond to topical minoxidil due to low SULT1A1 enzyme activity, but oral minoxidil can be effective. Tretinoin may enhance minoxidil's effectiveness, and some users prefer oral minoxidil despite side effects.
community Minoxidil aint shit, genetics are dumb, i dont want to be bald
Minoxidil alone is not effective for significant hair regrowth; combining it with finasteride or dutasteride is necessary. Additional treatments like hair transplants, microneedling, or oral medications are recommended for better results.
community Switched to oral minoxidil from topical 3 weeks ago, insane shedding.
Switching from topical to oral minoxidil led to significant hair shedding, with increased dutasteride usage possibly contributing. Users suggest that dosage changes can cause shedding, but hair often regrows stronger.
community How to Use Hair Moisturizer with Minoxidil: Timing and Compatibility?
You can use hair moisturizing creams with minoxidil, but it's best to wait before applying the cream to ensure minoxidil is absorbed.
Related Research
6 / 1000+ results
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men
5% minoxidil works better for hair growth and density, with minor irritation.
research Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery
Niosomes improve minoxidil skin delivery for hair loss treatment.
research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss
5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.
research Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells
Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
research Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension
Minoxidil effectively lowers blood pressure with few side effects.