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    Hair Growth Induced by Blockade of Macrophage-Derived Oncostatin M and Downstream JAK-STAT5 Signaling in Hair Follicle Stem Cells

    April 2018 in “ Journal of Investigative Dermatology ”
    E. Wang, Angela M. Christiano
    Studysummary This study identified a specific subset of macrophages as a key source of oncostatin M, maintaining hair follicle stem cell quiescence during the resting phase in mice, suggesting a potential target for treating hair disorders.
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    Related research 6

    1. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Dermal Sheath Cells Contribute to Postnatal Hair Follicle Growth and Cycling Journal of Dermatological Science · 2016
    4. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    6. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996