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    Did you mean Small Molecule Inhibitor?
    Glossary Small Molecule Inhibitor

    blocks specific proteins or enzymes within cells

    A Small Molecule Inhibitor (SMI) is a type of drug that can enter cells easily due to its low molecular weight and can interfere with specific proteins or enzymes to block their activity. These inhibitors are often used in treatments for various diseases, including cancer and autoimmune disorders, by targeting and disrupting specific pathways that contribute to disease progression.

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    Research 10 of 1000+

    1. Biologic Therapies and Small-Molecule Inhibitors for Dissecting Cellulitis of the Scalp: A Systematic Review Dermatology and Therapy · 2026
    2. A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment Orphanet Journal of Rare Diseases · 2025
    3. Small Molecule Inhibitors and Inflammatory Skin Diseases Suez Canal University Medical Journal · 2018
    4. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    5. A Small Molecule Inhibitor Partitions Two Distinct Pathways for Trafficking of Tonoplast Intrinsic Proteins in Arabidopsis PloS one · 2012 · 35 citations
    6. Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened Clinical cancer research · 2011 · 63 citations
    7. HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells <i>in vitro</i> Molecular Medicine Reports · 2021 · 7 citations
    8. Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened 2023
    9. Biologics and Small Molecules for Inflammatory Nail Disorders: A Narrative Review Indian Dermatology Online Journal · 2024 · 1 citations
    10. A machine learning and network framework to discover new indications for small molecules bioRxiv (Cold Spring Harbor Laboratory) · 2019
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    Learn 2 of 37

    1. PP405 mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
    2. Adenosine Molecule the body uses for energy, used as a cosmetic hair-lotion ingredient
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