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    Glossary Quiescence

    state of cellular dormancy without active division

    Quiescence refers to a state of inactivity or dormancy in cells, where they are not actively dividing but are still metabolically active. In the context of hair biology, hair follicle stem cells can enter a quiescent state, pausing their growth and division until they receive signals to re-enter the active phase of the hair growth cycle. This process is crucial for maintaining the long-term health and regenerative capacity of hair follicles.

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    1. The ending of alopecia? Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Reddit · 30 Oct 2021
    2. "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle" Reddit · 27 Aug 2025
    3. Relax to grow more hair. Study title: Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Reddit · 31 Mar 2021

    Research 10 of 1000+

    1. Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity Nature Reviews Molecular Cell Biology · 2023 · 200 citations
    2. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    3. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Science · 2016 · 142 citations
    4. Stem cell quiescence acts as a tumour suppressor in squamous tumours Nature Cell Biology · 2013 · 66 citations
    5. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    6. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    7. Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence Journal of Investigative Dermatology · 2015 · 24 citations
    8. Stem Cells on Alert: Priming Quiescent Stem Cells after Remote Injury Cell stem cell · 2014 · 13 citations
    9. Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms Nature Communications · 2024 · 11 citations
    10. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
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