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GlossaryQuiescent State

period when cells are inactive or not dividing

The quiescent state, also known as the resting state, refers to a period during which cells or tissues are inactive or not undergoing active growth and division. In the context of hair biology, this is often associated with the telogen phase of the hair growth cycle, where hair follicles are not actively producing new hair but are instead in a state of rest before shedding and eventually re-entering the growth phase.

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research Hdac1 and Hdac2 Regulate the Quiescent State and Survival of Hair-Follicle Mesenchymal Niche

1 citations, August 2023 in “Nature communications”

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

research Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hedgehog Signaling Pathway

29 citations, January 2017 in “Journal of Investigative Dermatology”

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing

126 citations, August 2018 in “Molecular Systems Biology”

Fibroblast state switching is crucial for skin healing and development.

research Factors Regulating Quiescent Stem Cells: Insights from the Intestine and Other Self-Renewing Tissues

8 citations, December 2015 in “The Journal of Physiology”

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

research Niche Required for Inducing Quiescent Stem Cells

19 citations, January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”

A special environment is needed to fully activate sleeping stem cells.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.