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    Glossary Quiescent State

    period when cells are inactive or not dividing

    The quiescent state, also known as the resting state, refers to a period during which cells or tissues are inactive or not undergoing active growth and division. In the context of hair biology, this is often associated with the telogen phase of the hair growth cycle, where hair follicles are not actively producing new hair but are instead in a state of rest before shedding and eventually re-entering the growth phase.

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    1. Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche Nature communications · 2023 · 1 citations
    2. Msi2 Maintains Quiescent State of Hair Follicle Stem Cells by Directly Repressing the Hh Signaling Pathway Journal of Investigative Dermatology · 2017 · 29 citations
    3. Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State Stem Cells · 2013 · 31 citations
    4. Fibroblast state switching orchestrates dermal maturation and wound healing Molecular Systems Biology · 2018 · 126 citations
    5. H2AK119ub dynamics control hair follicle stem cell quiescence Nature Communications · 2025 · 2 citations
    6. State-dependent signaling by Ca<sub>v</sub>1.2 regulates hair follicle stem cell function Genes & development · 2013 · 27 citations
    7. Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011 · 191 citations
    8. Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior Cold Spring Harbor Perspectives in Medicine · 2014 · 42 citations
    9. Editorial: Hair Follicle Stem Cell Regeneration in Aging Frontiers in Cell and Developmental Biology · 2021 · 4 citations
    10. The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function Oncogene · 2022 · 3 citations
    11. Stem cell quiescence acts as a tumour suppressor in squamous tumours Nature Cell Biology · 2013 · 66 citations
    12. The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse Stem cell research & therapy · 2022 · 2 citations
    13. Is There a Histone Code for Cellular Quiescence? Frontiers in Cell and Developmental Biology · 2021 · 27 citations
    14. The role of metabolism in cellular quiescence Journal of Cell Science · 2023 · 18 citations
    15. Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model · 2017 · 3 citations
    16. Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging Frontiers in Aging · 2023 · 3 citations
    17. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    18. Stem Cells on Alert: Priming Quiescent Stem Cells after Remote Injury Cell stem cell · 2014 · 13 citations
    19. Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity Nature Reviews Molecular Cell Biology · 2023 · 200 citations
    20. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    21. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    22. Integrative Whole-Transcriptome Sequencing Analysis of Skin Tissues with Different Coat Types in Cashmere Goats Across Stages of Hair Follicle Development 2026
    23. Quiescent and aging hair follicle stem cells Science · 2016
    24. Data from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy 2023
    25. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019 · 101 citations
    26. The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the hair follicle stem cell transcriptome Frontiers in cell and developmental biology · 2023
    27. 1359 Hair growth is induced by blockade of macrophage-derived oncostatin M and downstream JAK-STAT5 signaling in hair follicle stem cells Journal of Investigative Dermatology · 2018
    28. Modeling of ionizing radiation induced hair follicle regenerative dynamics Journal of Theoretical Biology · 2022
    29. Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration PLoS Genetics · 2021 · 6 citations
    30. Paneth Cells in Intestinal Homeostasis and Tissue Injury PLoS ONE · 2012 · 146 citations