Editorial: Hair Follicle Stem Cell Regeneration in Aging

    November 2021 in “ Frontiers in Cell and Developmental Biology ”
    Mingxing Lei, Sung‐Jan Lin, Cheng‐Ming Chuong
    Studysummary Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 24

    1. Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth Frontiers in Cell and Developmental Biology · 2021
    2. Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in In Vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures Frontiers in cell and developmental biology · 2021
    3. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021
    4. Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging Frontiers in Cell and Developmental Biology · 2021
    5. Dietary Vitamin A Impacts Refractory Telogen Frontiers in Cell and Developmental Biology · 2021
    6. Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures Frontiers in cell and developmental biology · 2021
    7. Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia Frontiers in Cell and Developmental Biology · 2021
    8. MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells Frontiers in cell and developmental biology · 2020
    9. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020
    10. Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells Frontiers in Cell and Developmental Biology · 2020
    11. Two-Cell Assemblage Assay: A Simple In Vitro Method for Screening Hair Growth-Promoting Compounds Frontiers in Cell and Developmental Biology · 2020
    12. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020
    13. Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging Frontiers in Cell and Developmental Biology · 2020
    14. Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes Frontiers in Cell and Developmental Biology · 2020
    15. IL-36α Promoted Wound-Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation Frontiers in Cell and Developmental Biology · 2020
    16. Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells In Vitro by Forming a Complex With Tcf4 and β-Catenin Frontiers in Cell and Developmental Biology · 2020
    17. Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1 Frontiers in Cell and Developmental Biology · 2020
    18. Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials Experimental Dermatology · 2018
    19. Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells Proceedings of the National Academy of Sciences of the United States of America · 2017
    20. Aging, Alopecia, and Stem Cells Science · 2016
    21. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    22. Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4 Journal of Investigative Dermatology · 2014
    23. New Hair From Healing Wounds Nature · 2007
    24. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007

    Related research 2

    1. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    2. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001