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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Dormancy in the Stem Cell Niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research HDAC6-Dependent Deacetylation of NGF Dictates Its Ubiquitination and Maintains Primordial Follicle Dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.
research Basal Cell Carcinomas Acquire Secondary Mutations to Overcome Dormancy and Progress from Microscopic to Macroscopic Disease
Basal cell carcinomas need extra mutations to grow from small to large tumors.
research Stem Cell Niche: From Concept to Reality
Stem cell niches are crucial for maintaining stem cells, with Paneth cells and TGF-beta playing key roles.
research The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity
The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
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5 / 22 resultscommunity Finally, some real breakthroughs. A comparison of the two leading baldness treatments: PP405 versus ABS-201
PP405 and ABS-201 are promising treatments for male pattern baldness. PP405 shows rapid hair growth in human trials, while ABS-201 shows significant regrowth in animal studies but is still in early human trials.
community 7 Months on 1.5mg of fin. 1st pic in March and 2nd one is from yesterday. Are these gains or is it because my hair is just longer?
A user shared progress pictures after 7 months on 1.5mg of finasteride, showing significant hair improvement. The user clarified they split 5 mg pills into quarters, resulting in a 1.33 mg dose.
community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells
PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.
community Regretting my hair transplant — 5 months in and still patchy/thin
The user regrets their hair transplant after 5 months due to patchy and thin hair, despite starting finasteride at the same time. Many recommend waiting 12-18 months for results and using finasteride and minoxidil before and after the transplant.
community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.