TLDR Erythropoietin helps hair grow and could be a potential treatment for hair loss.
In the 2010 study, erythropoietin (EPO) was shown to stimulate hair growth by promoting the proliferation of dermal papilla cells (DPCs) and elongating hair shafts in cultured human hair follicles, as well as inducing and prolonging the anagen phase in mice. EPO treatment led to increased cell viability and proliferation, particularly noted by a rise in Ki-67-positive matrix keratinocytes, which are markers of cell proliferation. The expression of EPO and its receptor (EPOR) was found to be highest during the anagen phase of the hair cycle. These findings suggest that EPO and its analogs could be potential treatments for hair loss conditions, as they can modulate hair growth through the stimulation of DPCs that express functional EPOR. The research was funded by the Korea Research Foundation Grant and the Korean Ministry of Education, Science and Technology.
34 citations,
June 2009 in “British journal of dermatology/British journal of dermatology, Supplement” Vitamin C derivative helps hair grow longer by making cells produce a growth factor through a specific cellular pathway.
171 citations,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
78 citations,
August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
211 citations,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
745 citations,
February 1992 in “Trends in genetics” Hair follicles create different cell layers and proteins, controlled by various molecules.
17 citations,
May 2010 in “Journal of Dermatological Science” Erythropoietin helps hair grow and could be a potential treatment for hair loss.
