Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia

    A. Premanand, B. Reena Rajkumari
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    TLDR Androgens may block hair growth signals, targeting this could treat hair loss.
    This document from 5 years ago explores the relationship between androgens and hair loss in androgenetic alopecia. It suggests that androgens can inhibit the Wnt/β-catenin signaling pathway, which is important for hair growth, and proposes targeting this pathway as a potential treatment for the condition. The document also discusses the role of androgen receptors and dermal papilla cells in hair follicle development and regeneration. Overall, the paper highlights the need for further research to fully understand the molecular mechanisms of androgenetic alopecia and develop effective treatments.
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