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    Did you mean Skin Thickening?
    Glossary Skin Thickening

    process where skin becomes thicker due to chronic irritation

    Skin thickening, also known as lichenification, refers to the process where the skin becomes thicker and leathery due to chronic inflammation or repeated irritation. This condition often results from persistent scratching or rubbing, leading to an exaggerated skin cell production and a more pronounced skin texture. It is commonly seen in conditions like eczema or chronic dermatitis.

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    Research 30 of 1000+

    1. Ex Vivo Assessment of Heat and Humidity Effects on Human Skin and Potential Protection by Kombucha Tea Extract Cosmetics · 2026
    2. Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology American Journal of Clinical Dermatology · 2026
    3. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    4. Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase Journal of Investigative Dermatology · 2001 · 54 citations
    5. Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation Scientific Reports · 2017 · 27 citations
    6. Dorsal skin responses to subchronic ultraviolet B (UVB)-irradiation in Wistar-derived hypotrichotic WBN/ILA-Ht rats. PubMed · 2002 · 7 citations
    7. Correction: RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 4 citations
    8. 915 Dietary grape powder inhibits atopic dermatitis-like skin lesions in NC/Nga mice Journal of Investigative Dermatology · 2019
    9. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    10. miR-3606-3p alleviates skin fibrosis by integratively suppressing the integrin/FAK, p-AKT/p-ERK, and TGF-β signaling cascades Journal of Advanced Research · 2024 · 15 citations
    11. Tracing the Change and Contribution of Subcutaneous Adipose to Skin Expansion Using a Luciferase-Transgenic Fat Transplantation Model Plastic & Reconstructive Surgery · 2023 · 4 citations
    12. Hair follicle micro-particle skin grafting induces scar remodeling via PI3K-AKT signaling: a randomized clinical trial npj Regenerative Medicine · 2026
    13. Ichthyosis follicularis with alopecia and photophobia in a mother and daughter 2000 · 36 citations
    14. Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs 2021 · 12 citations
    15. The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function 2013 · 1 citations
    16. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 Development · 2010 · 34 citations
    17. Anti-allergic Effects Of Fertilized Red Ginseng Marc On 2,4-dinitrochlorobenzene-induced Atopic Dermatitis-like Mice Model Preprints.org · 2022 · 2 citations
    18. Case report: Systemic granulomatous disease with vasculitis in a bull due to hairy vetch (Vicia villosa) toxicosis ˜The œBovine practitioner · 2023
    19. Characterization of an autoimmune condition associated with AEC syndrome 2016
    20. Establishment of a murine cGVHD model with scleroderma Junshi yixue · 2011
    21. Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures Frontiers in cell and developmental biology · 2021 · 5 citations
    22. A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome 2002 · 152 citations
    23. Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations 2011 · 41 citations
    24. Micro-Current Stimulation Has Potential Effects of Hair Growth-Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model International Journal of Molecular Sciences · 2021 · 16 citations
    25. Effects of RF Electric Currents on Hair Follicle Growth and Differentiation: A Possible Treatment for Alopecia International Journal of Molecular Sciences · 2024
    26. 092 Novel biallelic RIPK4 mutations cause ectodermal dysplasia with cutaneous syndactyly 2019
    27. Prevalance, clinical characteristics, possible etiological and diagnostic approach in dogs with acral lick dermatitis Exploratory animal and medical research · 2022
    28. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    29. Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion Cancer research · 2012
    30. Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study Lasers in medical science · 2024