169 citations
,
January 2018 in “Cell Reports” In this study, researchers successfully derived skin organoids from mouse pluripotent stem cells that spontaneously produce hair follicles, potentially aiding in hair growth research and in vitro drug testing.
3 citations
,
January 2017 in “Methods in molecular biology” This book reviews organogenesis in developmental biology and next-generation organ regenerative therapy but reports no new research findings.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
256 citations
,
October 2013 in “Nature Communications” This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.
165 citations
,
October 2013 in “Nature Communications” This study demonstrates that bioengineered salivary gland transplants can fully regenerate gland function, producing saliva and restoring normal swallowing in salivary gland-defective mice, offering potential for xerostomia treatment.
179 citations
,
April 2012 in “Nature Communications” This study demonstrates the potential of using bioengineered follicles from adult tissue-derived stem cells for fully functional hair regeneration, illustrating possible applications in organ replacement therapy.
36 citations
,
August 2009 in “PubMed” This article discusses different types of hair loss, their potential causes, and treatment options, but it reports no new clinical findings; the authors emphasize the importance of considering the emotional impact on patients.
759 citations
,
February 2009 in “Current Biology” This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
788 citations
,
February 2007 in “Nature” This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
745 citations
,
February 1992 in “Trends in genetics” This article describes the potential role of various growth factors and molecules in regulating mammalian hair follicle development but does not present new experimental results.