Positive Impact of Fish Oil on Diabetic and Hypercholesterolemic Skin Disorders

The document from 2015 discusses the structure of the integumentary system, including the epidermis and dermis, and the role of various cells and structures within it, such as hair follicles, sweat glands, and immune cells. It highlights the importance of elements like calcium, potassium, lipid, and cholesterol in maintaining epidermal permeability. The paper emphasizes that an overload of cholesterol can lead to negative effects on cell structure, hair follicle formation, and keratinocyte formation, which in turn impairs keratinization. It concludes by stating the benefits of fish oil, particularly its components eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in promoting skin health. These components are said to enhance permeability, growth, and differentiation of the stratum corneum, as well as inhibit proinflammatory cytokines, thereby improving complications associated with diabetes and hypercholesterolemia.