Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration

    March 2020 in “ International Journal of Molecular Sciences ”
    Hamidreza Ahmadi-Ashtiani, Parisa Bishe, Anna Baldisserotto … Silvia Vertuani
    Studysummary This article reviews advanced strategies for enhancing drug delivery to cutaneous stem cells to improve treatment for skin conditions and reports no new experimental findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 21

    1. Role of Bulge Epidermal Stem Cells and TSLP Signaling in Psoriasis EMBO molecular medicine · 2019
    2. Topical Delivery of Drugs Using Ethosomes: A Review Indian drugs · 2019
    3. Priming Mobilization of Hair Follicle Stem Cells Triggers Permanent Loss of Regeneration After Alkylating Chemotherapy Nature Communications · 2019
    4. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    5. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    6. Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation Nature cell biology · 2017
    7. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    8. Familial Frontal Fibrosing Alopecia Treated With Dutasteride, Minoxidil, and Artificial Hair Transplantation Australasian Journal of Dermatology · 2016
    9. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015
    10. Modulating the Stem Cell Niche for Tissue Regeneration Nature Biotechnology · 2014
    11. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    12. Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid Molecular Therapy · 2014
    13. Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress International Journal of Cosmetic Science · 2013
    14. Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane 2012
    15. Anatomy and Physiology of the Skin Journal of the Dermatology Nurses’ Association · 2011
    16. Human Dermal Stem Cells Differentiate Into Functional Epidermal Melanocytes Journal of Cell Science · 2010
    17. Evaluation of the Permeability of Hair Growing Ingredient Encapsulated PLGA Nanospheres to Hair Follicles and Their Hair Growing Effects Bioorganic & Medicinal Chemistry Letters · 2007
    18. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    19. Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles Journal of controlled release · 2004
    20. Ethosomes: New Prospects in Transdermal Delivery Critical Reviews in Therapeutic Drug Carrier Systems · 2003
    21. Efficient Delivery of Transgenes to Human Hair Follicle Progenitor Cells Using Topical Lipoplex Nature biotechnology · 2000

    Related research 5

    1. Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration PubMed · 2019
    2. Isolation of Mouse Hair Follicle Bulge Stem Cells and Their Functional Analysis in a Reconstitution Assay Methods in molecular biology · 2016
    3. Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications International Journal of Molecular Sciences · 2015
    4. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012
    5. Skin and Hair: Models for Exploring Organ Regeneration Human Molecular Genetics · 2008