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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Blocking certain immune signals can reduce skin damage from radiation therapy.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

Mechanical forces are crucial for shaping cells and forming tissues during development.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Thyroid function affects skin health, with a complex interaction between the two.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

A mutation in the FAM83G gene is linked to skin and hair abnormalities in two related individuals.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Hair growth environment recreated with challenges; stem cells make successful skin organoids.

Cannabinoids might help treat skin problems but more research is needed to be sure.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Thyroid hormone may be useful for treating various skin conditions and needs more research.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

WNT signaling is crucial for skin development and healing.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Zebrafish are useful for studying and developing treatments for human skin diseases.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.