Dermatological Manifestations Associated With Pregnancy

    August 2009 in “ Expert Review of Dermatology ”
    Boutros Soutou, Dany Nassar, S. Régnier, Olivier Parant, Kiarash Khosrotehrani, S. Aractingi
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    TLDR Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.
    The document from August 1, 2009, reviews dermatological conditions associated with pregnancy, including physiological changes, specific dermatoses, and other skin-related issues. Physiological changes such as hyperpigmentation, vascular changes, and striae gravidarum are common due to hormonal and other systemic changes in pregnancy. Specific dermatoses like polymorphic eruption of pregnancy (PEP), pemphigoid gestationis (PG), and atopic eczema of pregnancy (AEP) are also discussed, with PEP being associated with a higher prevalence of male babies and a higher risk of Caesarean section. The document emphasizes the importance of skin biopsy and immunofluorescence for diagnosis, and treatments ranging from topical steroids to systemic corticosteroids. Intrahepatic cholestasis of pregnancy (ICP) is highlighted as a significant condition due to fetal risk, with treatments including cholestyramine and ursodeoxycholic acid. The document concludes that while the pathogenesis of many pregnancy dermatoses remains unclear, proper diagnosis and management are essential for maternal and fetal health.
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