Dermatological Manifestations Associated With Pregnancy

    August 2009 in “ Expert Review of Dermatology
    Boutros Soutou, Dany Nassar, S. Régnier, Olivier Parant, Kiarash Khosrotehrani, S. Aractingi
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    Studysummary This review examines physiological changes and dermatoses during pregnancy and reports no clinical results, highlighting the importance of recognizing these conditions for appropriate management.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document from August 1, 2009, reviews dermatological conditions associated with pregnancy, including physiological changes, specific dermatoses, and other skin-related issues. Physiological changes such as hyperpigmentation, vascular changes, and striae gravidarum are common due to hormonal and other systemic changes in pregnancy. Specific dermatoses like polymorphic eruption of pregnancy (PEP), pemphigoid gestationis (PG), and atopic eczema of pregnancy (AEP) are also discussed, with PEP being associated with a higher prevalence of male babies and a higher risk of Caesarean section. The document emphasizes the importance of skin biopsy and immunofluorescence for diagnosis, and treatments ranging from topical steroids to systemic corticosteroids. Intrahepatic cholestasis of pregnancy (ICP) is highlighted as a significant condition due to fetal risk, with treatments including cholestyramine and ursodeoxycholic acid. The document concludes that while the pathogenesis of many pregnancy dermatoses remains unclear, proper diagnosis and management are essential for maternal and fetal health.
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