Dermatoses of Pregnancy

    George Kroumpouzos, Lisa M. Cohen
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    TLDR Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
    The 2001 document reviews the classification of dermatoses during pregnancy, detailing various skin changes and diseases that can be affected by or specific to pregnancy. It discusses physiologic changes like pigmentary, hair, nail, glandular, connective tissue, and vascular changes. It also covers how pregnancy can affect inflammatory disorders like atopic dermatitis and psoriasis, infections such as Candida vaginitis and genital herpes, autoimmune disorders like systemic lupus erythematosus, metabolic disorders, connective tissue disorders, and tumors like pyogenic granuloma and skin tags. The document notes that conditions like neurofibromas and melanocytic nevi may change during pregnancy, but there is no conclusive evidence of increased malignant transformation risk in nevi. It also discusses intrahepatic cholestasis of pregnancy and specific dermatoses like Herpes Gestationis and Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP), the latter being the most common gestational dermatosis. PUPPP affects 1 in 130 to 1 in 300 pregnancies, usually in primigravidas, and is self-limited with a mean duration of 6 weeks. The document emphasizes the importance of correct diagnosis and management of these conditions for the health of both mother and fetus.
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