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    GlossaryMoles

    clusters of pigmented skin cells, often called nevi

    Moles, also known as nevi, are common skin growths that appear when melanocytes, the cells responsible for producing pigment, grow in clusters. They can vary in color from flesh-toned to dark brown and may be flat or raised. While most moles are benign, changes in their size, shape, or color can sometimes indicate skin cancer, making regular monitoring important.

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      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community New potential hair loss treatment (news release)

      in Treatment  186 upvotes 4 years ago
      New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 8 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.