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GlossaryImmunostaining (Immunofluorescence)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research Detection of Bim and Puma in Mouse Hair Follicles Using Immunofluorescence and TUNEL Assay Double Staining

3 citations, July 2015 in “Biotechnic & histochemistry”

Bim and Puma proteins are found in developing mouse hair follicles and are involved in more than just cell death.

Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

research Co-Expression Pattern of Artemis Serine 516 Phosphorylation with Indicators in Differentiation, Proliferation, and Apoptosis of Human Anagen Hair Follicles: An Immunofluorescence Double-Staining Study

January 2023 in “Frontiers in bioscience”

Artemis protein may help control hair growth and health by influencing cell processes.

Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test Using Indirect Immunofluorescence Method

research Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test Using Indirect Immunofluorescence Method

28 citations, April 2009 in “Annals of laboratory medicine”

The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.

Role of Direct Immunofluorescence on Outer Root Sheath of Hair Follicle in Monitoring Disease Activity of Pemphigus Vulgaris

research Role of Direct Immunofluorescence on Outer Root Sheath of Hair Follicle in Monitoring Disease Activity of Pemphigus Vulgaris

1 citations, September 2017 in “Journal of Pathology of Nepal”

Testing hair roots with a special dye is a simple, non-invasive way to check disease progress in pemphigus vulgaris patients.

research Comparison of Sensitivity Patterns of Direct Immunofluorescence on Perilesional Skin and Plucked Hair in Pemphigus Vulgaris

June 2017 in “Journal of the American Academy of Dermatology”

Plucked hair can help diagnose pemphigus vulgaris early.

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