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Glossary Stretch Marks

long, narrow streaks on skin from rapid stretching or growth

Stretch marks, also known as striae or striae distensae, are long, narrow streaks or lines that develop on the skin when it is stretched rapidly, such as during pregnancy, rapid weight gain, or growth spurts. They occur when the dermis, the middle layer of the skin, is torn due to the stretching, leading to the formation of scar tissue. Initially, they may appear red or purple but often fade to a silvery-white color over time.

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Research

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research Effectiveness of an Autologous Micrografting Technology for Treating Stretch Marks

June 2025 in “Journal of Cosmetic Dermatology”

This study reports that autologous micrografting may effectively treat stretch marks by promoting extracellular matrix remodeling and enhancing fibroblast activity, potentially expanding therapeutic options for this condition.

research Micro needling in treatment of stretch marks

July 2023 in “International journal of dermatology, venereology and leprosy sciences”

This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.

research Obesity and the skin

128 citations , September 2011 in “British Journal of Dermatology”

Obesity is linked to various skin problems and may increase the risk of skin cancer.

research Physiological changes in the skin during pregnancy

96 citations , January 1997 in “Clinics in Dermatology”

This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.

research Microneedling: Where do we stand now? A systematic review of the literature

92 citations , June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery”

This review found that microneedling appears to be a safe and effective option for treating scars and wrinkles, with fewer side effects and shorter recovery time than some other treatments.

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Learn

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learn Scalp Micropigmentation

Can scalp micropigmentation hide my scars? Providers say SMP can make scalp scars much less visible, but not invisible; this is a provider claim, not a measured result.

Community Join

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community Has anyone ordered JXL-069 (grey market PP405)?

53 upvotes 1 year ago

People are discussing JXL-069 (PP405) for hair loss, with some experimenting with a 0.05% topical gel. Concerns about safety and efficacy persist due to limited testing and lack of official approval.

community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 11 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community Alright so FDA better approve PP405 as fast as they approved covid vaccine

129 upvotes 1 year ago

PP405 is a potential hair loss treatment showing promising early results, with hopes for market release by 2028, but skepticism remains due to inconclusive data and past disappointments with similar products. Current treatments like Minoxidil and Finasteride have side effects, leading some to anticipate PP405 as a safer alternative, though its effectiveness compared to placebo is debated.

community We got PP405 hair loss cure being one of the best inventions of 2025 time magazine before GTA 6

in Chat 162 upvotes 11 months ago

PP405 is discussed as a potential hair loss treatment, with doubts about its effectiveness and availability. Users mention using finasteride and minoxidil, and express concerns about PP405's cost and market release.

community How to properly use a dermaroller

7 upvotes 5 years ago

A female with suspected hair loss is considering using vitamins, a dermaroller, and essential oils to stimulate hair growth. Advice includes choosing a dermaroller with needles, preferably stainless steel.

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Clinics

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SMP
COSMETAT I Stretch Mark Camouflage & Cosmetic TattooVancouver, WA · US

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