The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth

    October 2022 in “ The Korean Journal of Physiology and Pharmacology ”
    Dong Wook Shin
    Studysummary This review discusses the roles of prostaglandins in hair loss and highlights their potential as targets for new alopecia treatments, but reports no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 48

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    2. Preparation of Topical Bimatoprost with Enhanced Skin Infiltration and In Vivo Hair Regrowth Efficacy in Androgenic Alopecia Drug Delivery · 2022
    3. Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial Clinical, Cosmetic and Investigational Dermatology · 2021
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    6. The Role of Prostaglandins in Androgenetic Alopecia International Journal of Dermatology · 2021
    7. Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study Journal of Cosmetic Dermatology · 2021
    8. HMGB1 Promotes Hair Growth via the Modulation of Prostaglandin Metabolism Scientific Reports · 2019
    9. Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women Journal of The European Academy of Dermatology and Venereology · 2019
    10. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women PubMed · 2018
    11. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018
    12. Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered to Overexpress Growth Factors Accelerate Outcomes in Hair Growth The Korean Journal of Physiology and Pharmacology · 2018
    13. Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders Acta dermato-venereologica · 2017
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    15. Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes Journal of Investigative Dermatology Symposium Proceedings · 2017
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    18. 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth Naunyn-Schmiedeberg's Archives of Pharmacology · 2016
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    23. Increased DHT Levels in Androgenic Alopecia Selected to Protect Men from Prostate Cancer Medical Hypotheses · 2014
    24. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    25. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    26. Efficacy and Safety of Bimatoprost 0.03% Versus Minoxidil 3% in Enhancement of Eyebrows: A Randomized, Double-Blind, Split-Face Comparative Study Journal of dermatology · 2012
    27. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
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    33. Latanoprost in the Treatment of Eyelash Alopecia in Alopecia Areata Universalis Journal of The European Academy of Dermatology and Venereology · 2009
    34. Successful Use of Bimatoprost in the Treatment of Eyelash Alopecia Clinical and Experimental Dermatology · 2009
    35. The Efficacy of Latanoprost in the Treatment of Alopecia Areata of Eyelashes and Eyebrows European Journal of Dermatology · 2009
    36. Lack of Efficacy of Topical Latanoprost and Bimatoprost Ophthalmic Solutions in Promoting Eyelash Growth in Patients with Alopecia Areata Journal of The American Academy of Dermatology · 2009
    37. Prostanoid Receptors in Anagen Human Hair Follicles Experimental dermatology · 2007
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    39. Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata Journal of The American Academy of Dermatology · 2005
    40. Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model Experimental dermatology · 2005
    41. Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia Upon Cyclooxygenase-2 Overexpression Journal of Investigative Dermatology · 2003
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    43. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    44. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    45. Cyclooxygenase-2 Overexpression in the Skin of Transgenic Mice Results in Suppression of Tumor Development PubMed · 2002
    46. Androgen Responsive Genes as They Affect Hair Growth PubMed · 2001
    47. Abnormal Differentiation of Epidermis in Transgenic Mice Constitutively Expressing Cyclooxygenase-2 in Skin Proceedings of the National Academy of Sciences · 2001
    48. Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost American Journal of Ophthalmology · 1997

    Related research 5

    1. The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth The Korean Journal of Physiology and Pharmacology · 2022
    2. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    3. Low-Level Laser Therapy for Treatment of Hair Loss Lasers in Surgery and Medicine · 2013
    4. Managing Hair Loss Current Therapeutics · 1998
    5. Topical Minoxidil (3%) in Extensive Alopecia Areata, Including Long-Term Efficacy Journal of The American Academy of Dermatology · 1987