15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth

    May 2016 in “ Naunyn-Schmiedeberg's Archives of Pharmacology ”
    Hyun Woo Joo, Yoo Ri Kang, Mi Hee Kwack, Young Kwan Sung
    Studysummary This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.
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    Research cited in this study 7

    1. Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness? Experimental Dermatology · 2014
    2. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    3. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    4. Prostanoid Receptors in Anagen Human Hair Follicles Experimental dermatology · 2007
    5. The Hair Cycle Journal of Cell Science · 2006
    6. The Hair Cycle Journal of Cell Science · 2006
    7. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003

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