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15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth

research 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth

11 citations , May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology”

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

2 citations , February 2019 in “Journal of Investigative Dermatology”

Higher levels of the DP2 receptor may lead to hair loss.

research Metabolic Pathways of Eicosanoids: Derivatives of Arachidonic Acid and Their Significance in Skin

January 2025 in “Cellular & Molecular Biology Letters”

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth

October 2022 in “The Korean Journal of Physiology and Pharmacology”

Targeting the PGD2-DP2 pathway may help treat hair loss.

research Understanding the Role of Prostaglandin E2 in Regulating Human Platelet Activity in Health and Disease

35 citations , May 2015 in “Thrombosis Research”

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

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community Why is there no feedback on pge2/setipiprant?

in Question 7 upvotes 9 years ago

The conversation questions the lack of feedback on the effectiveness of PGE2 and setipiprant for hair loss, despite their availability. The user is puzzled by the absence of reviews or results, whether positive or negative.

community dunno if it's growing anything but it's making my scalp red

in Technology 182 upvotes 2 years ago

Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.

community Still not sure why men think diet has nothing to do with hair loss when scientific is quite the opposite [Link]

27 upvotes 7 years ago

Diet can influence hair health, but male pattern baldness (MPB) is primarily genetic. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Can we have a thread that summarizes all treatments options in addition to the big 3 which we have some evidence for, their mechanism of action and whether they can be combined with the big 3(other than dermarolling)?

in Treatment 56 upvotes 7 years ago

The conversation discusses hair loss treatments beyond the commonly known three, focusing on separating effective treatments from myths. Dutasteride and low-dose oral Minoxidil are mentioned as having clinical evidence for increasing hair counts, but with potential side effects.

community Autoimmune issue?

in Question 2 upvotes 8 years ago

The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

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