The Hair Loss Encyclopedia

Search

for
Search:

GlossaryGPR44 (DP2 receptor)

protein receptor involved in immune response and inflammation

GPR44, also known as CRTH2 or the DP2 receptor, is a type of protein found on the surface of certain cells that plays a role in the body's immune response. It is involved in the process of inflammation and allergic reactions by binding to prostaglandin D2, a molecule that can cause symptoms like itching, swelling, and redness. This receptor is also being studied for its potential role in conditions like asthma and alopecia, where it may influence hair growth and immune system activity.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 75 results

Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

2 citations, February 2019 in “Journal of Investigative Dermatology”

Higher levels of the DP2 receptor may lead to hair loss.

Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells

research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells

18 citations, February 2018 in “International Journal of Molecular Sciences”

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth

October 2022 in “The Korean Journal of Physiology and Pharmacology”

Targeting the PGD2-DP2 pathway may help treat hair loss.

research Prostanoid Receptors in Anagen Human Hair Follicles

39 citations, November 2007 in “Experimental dermatology”

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth

research 15-Deoxy Prostaglandin J2, The Nonenzymatic Metabolite Of Prostaglandin D2, Induces Apoptosis In Keratinocytes Of Human Hair Follicles: A Possible Explanation For Prostaglandin D2-Mediated Inhibition Of Hair Growth

11 citations, May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology”

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

View more "dp2 receptor" in research →

Community Join

0 / 0 results

— no results