TLDR The study created a new hair loss treatment paste that regrows hair faster and with fewer side effects than minoxidil alone.
The study developed a treatment for androgenetic alopecia (AGA), a common hair loss condition, using a composite paste system. This system uses minoxidil-loaded nanoparticles and valproic acid, delivered through microchannels created in the skin by roller-microneedles. The paste is composed of carboxymethyl cellulose, hyaluronic acid, and polyvinylpyrrolidone. The combination of valproic acid, which stimulates hair follicle regrowth, and the microchannels created by the roller-microneedles, resulted in faster hair regeneration at a lower administration frequency in an AGA mouse model compared to using minoxidil alone. This method reduces the risk of infection from subcutaneous injection and significantly decreases the side effects of lower-dose minoxidil.View this study on sciencedirect.com →
New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
Polymer microneedles are a promising, painless alternative to traditional needles for delivering drugs through the skin.
PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.
Early diagnosis and treatment, like topical minoxidil, can prevent hair loss in children.
New dissolving and implantable microneedle patches have been created for a long-lasting, non-invasive delivery of the drug finasteride.
Microneedles help treat hair loss by improving hair surroundings and promoting growth.
Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.
miR-133b promotes hair growth and could be a potential treatment for hair loss.
DHT stops hair regrowth in mice, similar to human hair loss.
Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
FPHL is common in women, influenced by genetics and hormones, and can be treated with medications, laser therapy, or hair transplantation.
Taking spironolactone doesn't increase the chance of breast cancer coming back.
Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.
ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.
Minoxidil can cause a rare eye condition, but it was successfully treated with oral Eplerenone in one case.
Both Platelet-Rich Plasma and Minoxidil foam increase hair count in women with hair loss, but Minoxidil is more effective. However, women were more satisfied with Platelet-Rich Plasma treatment.
Substance from human umbilical cord blood cells promotes hair growth.
Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
LLLT is a safe, promising hair loss treatment, but more research needed.
A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.
Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
Dupilumab for skin problems might reactivate hair loss in some patients.
Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.
Alopecia is linked to various health and mental conditions, impacts life quality, and needs medical attention beyond its cosmetic effects.
Oxidative stress affects hair loss in men with androgenetic alopecia.
Valproic acid increases hair count in men with hair loss.
Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.
Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
5% minoxidil foam helps women with thinning hair.
The conclusion is that the best approach for treating Female Pattern Hair Loss is a combination of different treatments.
Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.