Fabrication of Composite Pastes with Minoxidil-Loaded Nanoparticles and Valproic Acid for Androgenetic Alopecia Treatment

    July 2023 in “ International Journal of Biological Macromolecules ”
    Peixin Li, Yanfang Sun, Lei Nie … Guohua Jiang
    Studysummary In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
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    Research cited in this study 45

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    2. Exploiting Recent Trends in the Treatment of Androgenic Alopecia Through Topical Nanocarriers of Minoxidil Aaps Pharmscitech · 2022
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    22. Low-Dose Oral Minoxidil as Treatment for Non-Scarring Alopecia: A Systematic Review International Journal of Dermatology · 2020
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    25. Spironolactone Use Does Not Increase the Risk of Female Breast Cancer Recurrence: A Retrospective Analysis Journal of The American Academy of Dermatology · 2020
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    Related research 9

    1. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    2. A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss Clinical and Experimental Dermatology · 2018
    3. 5% Minoxidil: Treatment for Female Pattern Hair Loss PubMed · 2015
    4. Effectiveness of Once Daily 5% Minoxidil Topical Foam in the Treatment of Women with Thinning Hair Due to Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2015
    5. Understanding and Management of Female Pattern Alopecia Facial Plastic Surgery · 2008
    6. Androgenetic Alopecia in Adolescents PubMed · 2003
    7. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    8. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    9. The Use of Minoxidil to Prevent Alopecia During Chemotherapy for Gynecologic Malignancies PubMed · 1991