1 citations
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September 2007 in “European journal of paediatric neurology” Low dose valproic acid treatment caused hair loss in a young patient.
1 citations
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December 1982 in “PubMed” In this study, sodium valproate as monotherapy stopped seizures in 50% of epileptic children and was most effective in primary generalized and photosensitive epilepsies with notable side effects.
85 citations
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April 2012 in “PLOS ONE” This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.
73 citations
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October 2001 in “Epilepsia” In this study, valproic acid treatment was associated with reduced biotinidase activity and improved skin lesions after biotin supplementation in children with seizures.
68 citations
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March 2018 in “Biomaterials” This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.