valine
Research
20 / 547 resultsresearch Sequence of the Intron/Exon Junctions of the Coding Region of the Human Androgen Receptor Gene and Identification of a Point Mutation in a Family with Complete Androgen Insensitivity
This study identified a mutation in the steroid-binding domain of the androgen receptor gene associated with complete androgen insensitivity syndrome, impairing male sexual development due to altered androgen receptor protein function.
research The Mouse Frizzy (Fr) And Rat ‘Hairless’ (FrCR) Mutations Are Natural Variants Of Protease Serine S1 Family Member 8 (Prss8)
This study concluded that the frizzy mutation in mice is linked to a T to A transversion in Prss8 and is orthologous to the 'hairless' mutation in rats.
research Prevalence of Nutritional Deficiencies in Hair Loss Among Indian Participants: Results of a Cross-Sectional Study
This study found that nutritional deficiencies, particularly in amino acids and certain micronutrients, are common in individuals with hair loss across all types of alopecia.
research A Mutation in MAP2 Is Associated With Prenatal Hair Follicle Density
In this study, a missense mutation in the MAP2 gene was found to be associated with reduced hair follicle density, leading to the hairless phenotype in pigs.
research The N- And C-Terminal End Groups Of Hair Keratin
This study identified the same N-terminal and C-terminal amino acids in human and horse hair as previously found in wool and feather keratin.
research Comparative Studies of Hair Shaft Components Between Healthy and Diseased Donors
This study examined hair mineral and free amino acid components in various diseases and found that when using effect size analysis, specific components related to diabetes and other conditions were identified, suggesting their potential as novel health indicators.
research Identification of VLDL as a Biomarker for Prewarning of Androgenic Alopecia
This study suggests that valine and certain VLDL subfractions are positively associated with androgenetic alopecia risk, while reverse analysis showed AGA does not affect these metabolites.
research Acrodermatitis Dysmetabolica With Concomitant Acquired Acrodermatitis Enteropathica in a Patient With Maple Syrup Urine Disease
This study discusses zinc's vital role in skin cell growth and how its deficiency can lead to acrodermatitis enteropathica, marked by symptoms like alopecia and dermatitis. It notes that similar symptoms appear in people with certain metabolic conditions, referred to as acrodermatitis dysmetabolica.
research Amino Acids Oral Treatment for the Amelioration of Skin, Hair, and Nails Conditions: An Open-Label Study
This study found that a food supplement improved skin moisturization, elasticity, and thickness, reduced telogen hair density, and enhanced nail status in women with mild-to-moderate aging signs after 84 days.
research Severe Form of Keratitis–Ichthyosis–Deafness (KID) Syndrome Associated with Septic Complications
This report documents a novel alanine to valine substitution in the GJB2 gene in a Japanese girl with severe keratitis–ichthyosis–deafness syndrome, suggesting a potential link to her severe recurrent infections and immunodeficiency.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
This study describes the first case of female pseudohermaphroditism due to a novel homozygous glucocorticoid receptor gene mutation, indicating possible pre- and postnatal virilization in affected females.
research Structure of Human Type II 5 Alpha-Reductase Gene
This study details the isolation and characterization of the human type II 5 alpha-reductase gene, which may play a role in male pseudohermaphroditism, prostate cancer, and benign prostatic hyperplasia.
research A Novel Mutation in the Connexin 26 Gene (GJB2) in a Child with Clinical and Histological Features of Keratitis-Ichthyosis-Deafness (KID) Syndrome
This study identified a new heterozygous mutation in the connexin 26 gene (c.263C>T; p.Ala88Val) in a premature neonate with KID syndrome, who later died from complications.
research Comparison of Artificial Sebum with Human and Hamster Sebum Samples
This study suggests that artificial sebum L may serve as an effective substitute for human sebum in drug transport studies, due to its similar physicochemical properties.
research Investigation of Drug Partition Property in Artificial Sebum
This study found that the sebum partition coefficient (K(sebum)) for some drugs differs from the stratum corneum partition coefficient (K(sc)), indicating its importance for targeted drug delivery into hair and sebaceous follicles.
research Diffusion Properties of Model Compounds in Artificial Sebum
This study found that drug transport through artificial sebum varies depending on the compound, suggesting that sebum-targeted delivery can be optimized by selecting compounds based on their distinct transport profiles in sebum versus skin.
research Alteration in Hair Texture Following Regrowth in Alopecia Areata
This study reports a case where a 13-year-old boy's hair texture changed to resemble his early childhood hair after regrowth from alopecia areata, with potential causes remaining uncertain.
research Effect of Plasmatherapy on the Immune Status of Patients with Vitiligo
In this study, plasmatherapy was found to improve immune status indicators in patients with vitiligo, particularly benefiting those with segmental vitiligo by normalizing immune markers and reducing IL-6 levels, suggesting its potential as an adjunct treatment to slow depigmentation progression.
research Androgen-Dependent Dermopathy in Women with Keloid Scars
This study found that acne and androgenic alopecia were prevalent in women with "true" keloids, suggesting hormonal imbalances may contribute to keloid formation.
research Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application
This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.