Biotin-Responsive Alopecia and Developmental Regression

    July 1979 in “ Lancet ”
    BrendanM. Charles, Gwilym Hosking, Anne Green, R. J. Pollitt, Kim Bartlett, L S Taitz
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    TLDR Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.
    The document described cases of biotin-responsive alopecia and developmental regression, focusing on a 10-month-old boy with dermatitis, alopecia, and severe hypotonia. Laboratory tests indicated a metabolic disorder, and treatment with oral biotin (5 mg twice daily) led to significant improvements, including hair regrowth and regained motor functions. The study emphasized the importance of biotin in treating certain metabolic disorders and suggested further research into biotin and B vitamins' roles in immune function. It also noted that some patients had a generalized defect in biotin metabolism, which could be restored with biotin, and suggested that the abnormalities might be due to defects in biotin absorption or transport rather than dietary deficiency.
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      community Reminder: Biotin supplementation is a scam.

      in Product  110 upvotes 2 years ago
      Biotin supplements are considered ineffective for hair loss and are not supported by evidence. People in the conversation have mixed experiences, with some noting benefits for nails and skin but not hair, while others continue to use biotin as part of their vitamin regimen.

      community We need to keep these snake oil companies accountable.

      in Treatment  120 upvotes 1 year ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

      community Sudden, rapid hair loss

       4 upvotes 10 years ago
      A 33-year-old male experienced sudden, rapid hair loss, possibly due to a reaction to mentholated shampoo and undiluted tea tree oil, with a history of seborrheic dermatitis. He is currently taking finasteride, vitamin D3, a multivitamin, and biotin, and is seeking further medical evaluation.

      community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

      in Research/Science  1 upvotes 1 week ago
      The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

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