53 citations
,
March 2003 in “Journal of Investigative Dermatology”
This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotintransport component.
This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.
In this study, researchers identified genetic variants in the PCCA and PRLR genes that are significantly associated with hair coat length in Brangus heifers, potentially contributing to more thermotolerant cattle.
55 citations
,
November 2019 in “Cellular and Molecular Gastroenterology and Hepatology”
This study found that oral biotin supplementation improved outcomes in a mouse model of inflammatory bowel disease by reducing inflammatory cytokine production and enhancing intestinal barrier integrity, suggesting potential therapeutic benefits for IBD patients.
The user experienced a noticeable hair transformation in two months using 2mg finasteride daily, minoxidil, Nizoral shampoo twice a week, and Biotin shampoo daily. They reported initial side effects from finasteride but saw quick results despite occasional hair shedding.
The user shared a positive update on their hair transplant journey one year after the procedure in Turkey, where they received 4,350 grafts. They started taking finasteride at the 6-month mark and also use biotin, B6, B12, and scalp oils to support hair growth.
A 30-year-old male with androgenic alopecia started using topical Minoxidil in 2018, Finasteride in 2020, and switched to oral Minoxidil and Dutasteride after Finasteride stopped working. He underwent hair transplants in 2022 and 2025, showing significant improvement in recent photos.
The user has been using oral finasteride, minoxidil, and biotin for 10 months, noticing some stabilization and thicker baby hairs but not as much progress as expected. They are considering adding topical minoxidil and possibly switching to dutasteride.
The user shared a 6-month update on using oral minoxidil and GHK-Cu for hair regrowth, noting significant improvement and increased confidence. Some commenters questioned the authenticity of the transformation, mentioning visible hair fibers, while others discussed the role of DHT blockers and religious perspectives.
How much biotin is too much biotin?The NIH Adequate Intake for adults is 30 mcg of biotin a day, and supplements often contain hundreds of times that; no toxic dose has been identified, but the FDA warns that high-dose biotin can distort blood tests including troponin, so tell your doctor and the lab before any test.