Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts

    Shingo Tajima, Akinobu Hayashi, Tadashi Suzuki, Takeji Nishikawa
    Studysummary This study suggests that minoxidil is a potent stimulator of elastin expression in embryonic skin fibroblasts, primarily affecting elastin mRNA levels, without impacting cell proliferation during the stationary phase.
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    Research cited in this study 12

    1. Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells Archives of Biochemistry and Biophysics · 1994
    2. Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine Journal of Investigative Dermatology · 1992
    3. Treatment of Female Androgenetic Alopecia with Minoxidil 2% International Journal of Dermatology · 1992
    4. Sulfation of Minoxidil in Keratinocytes and Hair Follicles and the Stimulatory Effect of Minoxidil on the Biosynthesis of Glycosaminoglycans Annals of the New York Academy of Sciences · 1991
    5. The Hair Growing Effect of Minoxidil Annals of the New York Academy of Sciences · 1991
    6. Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro Journal of Investigative Dermatology · 1991
    7. The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats Journal of Dermatology · 1990
    8. Electrophysiological Mechanisms of Minoxidil Sulfate-Induced Vasodilation of Rabbit Portal Vein Circulation Research · 1989
    9. Mechanism of Action of Minoxidil Sulfate-Induced Vasodilation: A Role for Increased Potassium Permeability PubMed · 1988
    10. Suppression of Fibroblast Proliferation and Lysyl Hydroxylase Activity by Minoxidil Journal of Biological Chemistry · 1987
    11. Direct Effects of Minoxidil on Epidermal Cells in Culture Journal of Investigative Dermatology · 1984
    12. Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension The New England Journal of Medicine · 1973

    Related research 1

    1. Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts Archives of Dermatological Research · 1995