Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension

July 1973 in “ The New England Journal of Medicine ”

William A. Pettinger, Helen J. Mitchell

TLDR Minoxidil effectively lowers blood pressure with few side effects.

Eleven patients with malignant or accelerated hypertension refractory to conventional drugs were treated with minoxidil as the primary antihypertensive agent. The blood pressure was reduced to or near normal levels in all patients, with remarkably few side effects. The use of minoxidil in managing hypertensive patients should be carefully weighed against the more heroic alternative nephrectomy and its consequences.

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research Minoxidil in Severe Hypertension with Renal Failure

100 citations, March 1973 in “American Journal of Cardiology”

Minoxidil effectively lowers blood pressure without major side effects.

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research The Cost Effectiveness of Topical Minoxidil Therapy in the Management of Baldness

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Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension

Research cited in this study

research Minoxidil in Severe Hypertension with Renal Failure

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Similar Research

research Comparison of a New 5% Minoxidil Foam and Rogaine in the Treatment of Androgenetic Alopecia in Chinese Men: A Randomized, Double-Blind, Phase III, Equivalence Trial

research The Penetration Enhancer SEPA Augments Stimulation of Scalp Hair Growth by Topical Minoxidil in the Balding Stumptail Macaque

research A Method for the Determination of Minoxidil in Hair-Regrowth Formulations by Micellar Electrokinetic Capillary Chromatography

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research The Cost Effectiveness of Topical Minoxidil Therapy in the Management of Baldness

research The Cost Effectiveness of Topical Minoxidil Therapy in the Management of Baldness