Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension
July 1973
in “
The New England Journal of Medicine
”
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Studysummary In this study, minoxidil effectively reduced blood pressure to near normal levels in patients with malignant or accelerated hypertension resistant to conventional treatments, offering a potential alternative to nephrectomy.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Eleven patients with malignant or accelerated hypertension refractory to conventional drugs were treated with minoxidil as the primary antihypertensive agent. The blood pressure was reduced to or near normal levels in all patients, with remarkably few side effects. The use of minoxidil in managing hypertensive patients should be carefully weighed against the more heroic alternative nephrectomy and its consequences.
