Comparison of a New 5% Minoxidil Foam and Rogaine in the Treatment of Androgenetic Alopecia in Chinese Men: A Randomized, Double-Blind, Phase III, Equivalence Trial

January 2023 in “ Dermatologic Therapy ”

Cheng Zhou, Weixin Fan, Jianfeng Zou, Jianglin Zhang, Hong Fang, Zhongfa Lv, Dingquan Yang, Wei Lai, Xinghua Gao, Qinping Yang, Aijun Chen, Jing Lou, Lili Zheng, Jianzhong Zhang

5% minoxidil foam Rogaine androgenetic alopecia hair density hair diameter nonvellus target area hair counts terminal to vellus hair ratio global photographic assessments adverse events NMF AGA

TLDR The new 5% minoxidil foam is as effective and safe as Rogaine® for treating hair loss in Chinese men.

The study compared a new 5% minoxidil foam (NMF) with Rogaine® in 417 Chinese men with androgenetic alopecia over 24 weeks. Both treatments showed similar increases in hair density and diameter, with no significant differences in nonvellus target area hair counts, hair diameter, terminal to vellus hair ratio, global photographic assessments, or adverse events. The results indicate that 5% NMF is as effective and safe as Rogaine® for AGA treatment, suggesting it could be a more accessible and economical option in China.

View this study on downloads.hindawi.com →

Discuss this study in the Community →

Research cited in this study

25 / 25 results

research Minoxidil: A Comprehensive Review

16 citations , June 2021 in “Journal of Dermatological Treatment”

Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.

research Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose

21 citations , March 2021

Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).

research Intradermal Injections With 0.5% Minoxidil for the Treatment of Female Androgenetic Alopecia: A Randomized, Placebo-Controlled Trial

7 citations , December 2020 in “Dermatologic Therapy”

Injections with 0.5% minoxidil effectively treat female hair loss, increasing hair density and thickness.

research Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety

59 citations , July 2020 in “Journal of The American Academy of Dermatology”

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

research A Review of the Treatment of Male Pattern Hair Loss

53 citations , February 2020 in “Expert Opinion on Pharmacotherapy”

Finasteride and minoxidil work best together for hair loss.

research Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia

52 citations , May 2019 in “Journal of The American Academy of Dermatology”

Low-dose oral minoxidil effectively improves male hair loss with mild side effects.

research Off-Label Use of Topical Minoxidil in Alopecia: A Review

32 citations , January 2019 in “American Journal of Clinical Dermatology”

Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.

Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

36 citations , September 2018 in “American Journal of Clinical Dermatology”

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

research A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia

43 citations , July 2018 in “Journal of The European Academy of Dermatology and Venereology”

Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.

Efficacy and Safety of a New 5% Minoxidil Formulation in Male Androgenetic Alopecia: A Randomized, Placebo-Controlled, Double-Blind, Noninferiority Study

research Efficacy and Safety of a New 5% Minoxidil Formulation in Male Androgenetic Alopecia: A Randomized, Placebo-Controlled, Double-Blind, Noninferiority Study

5 citations , April 2018 in “Journal of Cosmetic Dermatology”

New 5% minoxidil formula safely and effectively treats male hair loss.

research Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells

42 citations , February 2018 in “International Journal of Molecular Sciences”

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

145 citations , November 2017 in “Journal of The European Academy of Dermatology and Venereology”

Use minoxidil for hair loss treatment; assess results after 6 months.

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations , April 2017 in “Journal of The American Academy of Dermatology”

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

research Androgenetic Alopecia: An Update Of Treatment Options

110 citations , August 2016 in “Drugs”

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

research Effect of Minoxidil Topical Foam on Frontotemporal and Vertex Androgenetic Alopecia in Men: A 104-Week Open-Label Clinical Trial

20 citations , September 2015 in “Journal of The European Academy of Dermatology and Venereology”

Minoxidil foam promotes hair growth and reduces hair loss safely in men.

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

research A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Investigate the Efficacy and Safety of Minoxidil Topical Foam in Frontotemporal and Vertex Androgenetic Alopecia in Men

19 citations , January 2015 in “Skin Pharmacology and Physiology”

Minoxidil foam effectively promotes hair growth and reduces hair loss in men.

research Androgenetic Alopecia: An Evidence-Based Treatment Update

151 citations , May 2014 in “American Journal of Clinical Dermatology”

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

research Evidence for a Polygenic Contribution to Androgenetic Alopecia

26 citations , May 2013 in “British Journal of Dermatology”

Hair loss risk is influenced by multiple genes.

research Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness

75 citations , December 2011 in “British Journal of Dermatology”

Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.

A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women

research A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women

100 citations , June 2011 in “Journal of The American Academy of Dermatology”

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations , January 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

research Male Pattern Baldness: Current Treatments, Future Prospects

40 citations , July 2008 in “Drug Discovery Today”

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

142 citations , August 2007 in “Journal of The American Academy of Dermatology”

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men

112 citations , October 2005 in “Mayo Clinic Proceedings”

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

research Minoxidil: Mechanisms of Action on Hair Growth

397 citations , February 2004 in “British Journal of Dermatology”

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Related Research

7 / 7 results

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations , October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

1 citations , August 2022 in “JAAD case reports”

Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.

research Evaluation of the Effect of Autologous Platelet-Rich Plasma on Androgenic Alopecia

July 2020 in “Journal of Cosmetic and Laser Therapy”

Using your own platelet-rich plasma (PRP) can effectively treat hair loss, increasing hair density and width with no side effects.

research Platelet-Rich Plasma on Female Androgenetic Alopecia: Tested on 10 Patients

25 citations , April 2018 in “Journal of Cosmetic Dermatology”

PRP injections increase hair density and diameter in female androgenetic alopecia patients.

research Disorders of Hair

July 2013 in “DeckerMed Medicine”

The document's conclusion cannot be provided because the document is not readable or understandable.

research A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women

100 citations , June 2011 in “Journal of The American Academy of Dermatology”

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

research Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica

24 citations , February 1987 in “Drugs”

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.