MiRNA Microarray Profiling in Patients with Androgenic Alopecia and the Effects of miR-133b on Hair Growth

    December 2020 in “ Experimental and Molecular Pathology ”
    Wenjia Deng, Ting Hu, Le Han … Miaojian Wan
    Studysummary This study found that patients with androgenetic alopecia exhibit specific miRNA expression profiles, suggesting that abnormal miR-133b expression may inhibit the Wnt/β-catenin pathway and affect hair growth.
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    Research cited in this study 12

    1. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture Frontiers in Pharmacology · 2020
    2. MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2 Journal of cellular physiology · 2019
    3. Post-Transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation, and Hair Follicle Regression by miR-22 PLOS Genetics · 2015
    4. MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway Journal of Cell Biology · 2014
    5. The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: An Outpatient-Based Study Annals of Dermatology · 2013
    6. Characteristics of Androgenetic Alopecia in Asian Populations Annals of Dermatology · 2012
    7. Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle ˜The œFASEB journal · 2010
    8. Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities British Journal of Dermatology · 2010
    9. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    10. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006
    11. Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture Archives of Dermatological Research · 2005
    12. Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men Mayo Clinic Proceedings · 2005